- 专利标题： Inosine derivatives and production methods therefor
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申请号： US12847399申请日： 2010-07-30
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公开(公告)号： US08252920B2公开(公告)日： 2012-08-28
- 发明人: Takayoshi Torii , Kunisuke Izawa , Doo Ok Jang , Dae Hyan Cho
- 申请人： Takayoshi Torii , Kunisuke Izawa , Doo Ok Jang , Dae Hyan Cho
- 申请人地址： JP Tokyo
- 专利权人： Ajinomoto Co., Inc.
- 当前专利权人： Ajinomoto Co., Inc.
- 当前专利权人地址： JP Tokyo
- 代理机构： Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- 优先权： JP2003-170361 20030616
- 主分类号： C07H19/173
- IPC分类号： C07H19/173 ; C07H19/167 ; C07H19/16
摘要：
The present invention provides a method for producing an inosine derivative represented by the following general formula (1) including the steps of subjecting an inosine derivative of general formula (3) to dithiocarbonylation and carrying out radical reduction of the obtained compound. According to the present invention there can be produced compounds useful as anti-AIDS drugs on industrial scale. wherein R1 may be the same or different and are each benzyl group, benzhydryl group or trityl group, each of which may have a substituent in general formulas (1) and (3).
公开/授权文献
- US08288526B2 Inosine derivatives and production methods therefor 公开/授权日：2012-10-16
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