A framework for managing a lifecycle of a program in an organization is provided. The framework includes a process module, a guiding module, a program lifecycle mapping module, and a matrix module. The process module provides a plurality of process guidelines for the one or more stages of the project management lifecycle. Further, the process module includes a strategic planning module, a financial management module, a risk management module, an organization change management module, a stake holder management module, a knowledge management module, a contractual compliance module, a governance module and a program setup module. The guiding module integrates a plurality of organizational attributes with the process guidelines of the process module. The program lifecycle mapping module maps the plurality of process guidelines with the one or more stages of the life cycle. The matrix module provides assignment of program management roles to one or more participants.