发明授权
US08257755B2 Metabolic syndrome-improving agent and medicine, supplement, functional food and food additive containing the same 失效
代谢综合征改善剂和药物,补充剂,功能性食品和含有该食品的食品添加剂

  • 专利标题: Metabolic syndrome-improving agent and medicine, supplement, functional food and food additive containing the same
  • 专利标题(中): 代谢综合征改善剂和药物,补充剂,功能性食品和含有该食品的食品添加剂
  • 申请号: US11795638
    申请日: 2006-01-20
  • 公开(公告)号: US08257755B2
    公开(公告)日: 2012-09-04
  • 发明人: Takao SasakiMasamichi Yano
  • 申请人: Takao SasakiMasamichi Yano
  • 申请人地址: JP Kyoto
  • 专利权人: ARKRAY, Inc.
  • 当前专利权人: ARKRAY, Inc.
  • 当前专利权人地址: JP Kyoto
  • 代理机构: Morgan, Lewis & Bockius LLP
  • 优先权: JP2005-014385 20050121
  • 国际申请: PCT/JP2006/300865 WO 20060120
  • 国际公布: WO2006/077975 WO 20060727
  • 主分类号: A61K36/752
  • IPC分类号: A61K36/752 A61K31/235
Metabolic syndrome-improving agent and medicine, supplement, functional food and food additive containing the same
摘要:
A metabolic syndrome relieving agent that is free from a problem of side effects and can be taken for a long term is provided. Bergamottin is used as an agent for relieving a metabolic syndrome. Since bergamottin has functions of activating PPARα and PPARγ, promoting the secretion of adiponectin in adipocytes and inhibiting the generation of VLDLs in hepatic cells, it is possible to prevent or treat diseases such as insulin resistance, hyperinsulinism, type 2 diabetes, obesity, visceral fat obesity, hypertension, hyperlipemia, arteriosclerosis and the like and thus prevent or treat the metabolic syndrome. Also, as understood from the fact that citrus fruits such as a grapefruit or the like containing bergamottin have been eaten for many years, they have no problems in terms of safety and have a low calorie content, and therefore, they can be taken for a long term. Further, since bergamottin is tasteless and odorless, it does not impair the unique taste of a food when added to this food, so that it can be added to foods and taken.
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