Invention Grant
- Patent Title: Dithiolopyrrolone compounds, the preparation and the use thereof
- Patent Title (中): 二硫代罗环酮化合物，其制备及其应用
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Application No.: US12676470Application Date: 2008-08-29
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Publication No.: US08258176B2Publication Date: 2012-09-04
- Inventor: Guoping Wang , Quanhai Liu , Haiyan Sun , Wei Wu , Jian Hou , Lin Yao , Chungang Li , Minyu Liu , Fei Li , Xuejun Wu , Shuai Zhao
- Applicant: Guoping Wang , Quanhai Liu , Haiyan Sun , Wei Wu , Jian Hou , Lin Yao , Chungang Li , Minyu Liu , Fei Li , Xuejun Wu , Shuai Zhao
- Applicant Address: CN Shanghai CN Shanghai
- Assignee: Shanghai Institute of Pharmaceutical Industry,Shanghai Modern Pharmaceutical Co., Ltd.
- Current Assignee: Shanghai Institute of Pharmaceutical Industry,Shanghai Modern Pharmaceutical Co., Ltd.
- Current Assignee Address: CN Shanghai CN Shanghai
- Agency: Lowe, Hauptman, Ham & Berner, LLP
- Priority: CN200710045600 20070905
- International Application: PCT/CN2008/072207 WO 20080829
- International Announcement: WO2009/033396 WO 20090319
- Main IPC: A61K31/407
- IPC: A61K31/407 ; C07D487/04 ; C07D487/02
Abstract:
The invention discloses a dithiolopyrrolone compound represented by formula I or its pharmaceutically acceptable salts, wherein X1, R1, R2, R3, R4 are defined as in the description. The invention also discloses the preparation of such compounds, and the use of such compounds in preparation of medicaments for increasing peripheral white blood cells and in preparation of ancillary medicaments for inhibiting the decrease of peripheral white blood cells in radiotherapy or chemotherapy.
Public/Granted literature
- US20100210856A1 DITHIOLOPYRROLONE COMPOUNDS, THE PREPARATION AND THE USE THEREOF Public/Granted day:2010-08-19
Information query
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