发明授权
- 专利标题： Dehydroandrosterone analogs including an anti-inflammatory pharmacore and methods of use
- 专利标题（中）： 脱氢雄甾酮类似物，包括抗炎药物及其使用方法
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申请号： US12426889申请日： 2009-04-20
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公开(公告)号： US08258329B2公开(公告)日： 2012-09-04
- 发明人: Eric Anderson , Gary L. Bolton , Deborah A. Ferguson , Xin Jiang , Robert M. Kral, Jr. , Patrick M. O'Brien , Melean Visnick
- 申请人： Eric Anderson , Gary L. Bolton , Deborah A. Ferguson , Xin Jiang , Robert M. Kral, Jr. , Patrick M. O'Brien , Melean Visnick
- 申请人地址： US TX Irving
- 专利权人： Reata Pharmaceuticals, Inc.
- 当前专利权人： Reata Pharmaceuticals, Inc.
- 当前专利权人地址： US TX Irving
- 代理机构： Fulbright & Jaworski L.L.P.
- 主分类号： C07J1/00
- IPC分类号： C07J1/00 ; C07J21/00
摘要：
This invention provides novel compounds comprising the following anti-inflammatory pharmacore: wherein X, R1 and R2 are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.