发明授权
- 专利标题： Stilbene like compounds as novel HDAC inhibitors
- 专利标题（中）： 二苯乙烯类化合物作为新型HDAC抑制剂
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申请号： US12084430申请日： 2006-11-06
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公开(公告)号： US08263044B2公开(公告)日： 2012-09-11
- 发明人: Akella Satya Surya Visweswara Srinivas , Urkalan Kaveri Balan , Narayana Swamy Punthalir , Rama Swamy Velmurugan , Sriram Rajagopal , Gaddam Om Reddy , Virendra Kachhadia
- 申请人： Akella Satya Surya Visweswara Srinivas , Urkalan Kaveri Balan , Narayana Swamy Punthalir , Rama Swamy Velmurugan , Sriram Rajagopal , Gaddam Om Reddy , Virendra Kachhadia
- 申请人地址： IN Tamil-Nadu
- 专利权人： Orchid Research Laboratories Limited
- 当前专利权人： Orchid Research Laboratories Limited
- 当前专利权人地址： IN Tamil-Nadu
- 代理机构： Oliff & Berridge, PLC
- 优先权： IN1644/CHE/2005 20051110
- 国际申请： PCT/IB2006/003114 WO 20061106
- 国际公布： WO2007/054776 WO 20070518
- 主分类号： A61K9/12
- IPC分类号： A61K9/12 ; A61K31/427 ; A61K31/4409 ; C07D417/04 ; C07D213/56 ; A61P35/00
摘要：
The present invention relates to novel stilbene like compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and compositions, metabolites and prodrugs thereof. The present invention more particularly provides novel stilbene like compounds of the general formula (I). Also included is a method for treatment of cancer, psoriasis, proliferative conditions and conditions mediated by HDAC, in a mammal comprising administering an effective amount of a novel compound of formula (I) as described above.
公开/授权文献
- US20090136431A1 Stilbene Like Compounds as Novel HDAC Inhibitors 公开/授权日：2009-05-28
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