发明授权
US08263344B2 Compounds regulating calreticulin, KDEL receptor and/or Erp-57 cell surface exposure and uses thereof to evaluate the efficiency of a cancer treatment
失效
调节钙网蛋白,KDEL受体和/或Erp-57细胞表面暴露的化合物及其用途来评估癌症治疗的效率
- 专利标题: Compounds regulating calreticulin, KDEL receptor and/or Erp-57 cell surface exposure and uses thereof to evaluate the efficiency of a cancer treatment
- 专利标题(中): 调节钙网蛋白,KDEL受体和/或Erp-57细胞表面暴露的化合物及其用途来评估癌症治疗的效率
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申请号: US12438975申请日: 2007-09-07
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公开(公告)号: US08263344B2公开(公告)日: 2012-09-11
- 发明人: Guido Kroemer , Laurence Zitvogel , Theocharis Panaretakis
- 申请人: Guido Kroemer , Laurence Zitvogel , Theocharis Panaretakis
- 申请人地址: FR Villejuif Cedex FR Paris Cedex
- 专利权人: Institut Gustave Roussy,INSERM (Institut National de la Sante et de la Recherche Medicale)
- 当前专利权人: Institut Gustave Roussy,INSERM (Institut National de la Sante et de la Recherche Medicale)
- 当前专利权人地址: FR Villejuif Cedex FR Paris Cedex
- 代理机构: Saliwanchik, Lloyd & Eisenschenk
- 优先权: EP06291427 20060908; EP07300807 20070221
- 国际申请: PCT/EP2007/059417 WO 20070907
- 国际公布: WO2008/028968 WO 20080313
- 主分类号: G01N33/53
- IPC分类号: G01N33/53
摘要:
The present invention relates to a method for determining the susceptibility of a patient tumor cell to a cancer treatment, which method comprises the detection or measure of CRT, KDEL receptor and/or ERp57 on the surface of a tumor cell.
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