发明授权
US08263610B2 Substituted imidazolyl-5,6-dihydrobenzo[N]isoquinoline compounds
有权
取代的咪唑基-5,6-二氢苯并[N]异喹啉化合物
- 专利标题: Substituted imidazolyl-5,6-dihydrobenzo[N]isoquinoline compounds
- 专利标题(中): 取代的咪唑基-5,6-二氢苯并[N]异喹啉化合物
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申请号: US12649762申请日: 2009-12-30
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公开(公告)号: US08263610B2公开(公告)日: 2012-09-11
- 发明人: Syed M. Ali , Mark A. Ashwell , Chris Brassard , Audra Dalton , Anton Filikov , Jason Hill , Nivedita Namdev , Rocio Palma , Manish Tandon , David Vensel , Jianqiang Wang , Neil Westlund
- 申请人: Syed M. Ali , Mark A. Ashwell , Chris Brassard , Audra Dalton , Anton Filikov , Jason Hill , Nivedita Namdev , Rocio Palma , Manish Tandon , David Vensel , Jianqiang Wang , Neil Westlund
- 申请人地址: US MA Woburn
- 专利权人: ArQule, Inc.
- 当前专利权人: ArQule, Inc.
- 当前专利权人地址: US MA Woburn
- 代理机构: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- 代理商 Ivor R. Elrifi; Matthew Pavao, J.D.
- 主分类号: A01N43/42
- IPC分类号: A01N43/42 ; A61K31/44 ; C07D471/00 ; C07D491/00 ; C07D498/00 ; C07D513/00 ; C07D515/00
摘要:
The present invention relates to substituted imidazolyl-5,6-dihydrobenzo[n]isoquinoline compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted imidazolyl-5,6-dihydrobenzo[n]isoquinoline compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.
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