Techniques for performing channel and noise estimation for a MIMO transmission sent from multiple transmit antennas to multiple receive antennas are described. Samples are obtained from the receive antennas. For a first scheme, channel estimates are derived by correlating the samples with at least one pilot sequence, and signal, noise and interference statistics are also estimated based on the samples. For a second scheme, total received energy as well as signal and interference energy are estimated based on the samples. Noise is then estimated based on the estimated total received energy and the estimated signal and interference energy. For a third scheme, signal and on-time interference statistics are estimated based on the samples. Noise and multipath interference statistics are also estimated based on the samples. Signal, noise and interference statistics are then estimated based on the estimated signal and on-time interference statistics and the estimated noise and multipath interference statistics.