发明授权
US08269012B2 Aminopyrazole triazolothiadiazole inhibitors of c-met protein kinase
有权
c-met蛋白激酶的氨基吡唑三唑并噻二唑抑制剂
- 专利标题： Aminopyrazole triazolothiadiazole inhibitors of c-met protein kinase
- 专利标题（中）： c-met蛋白激酶的氨基吡唑三唑并噻二唑抑制剂
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申请号： US12788608申请日： 2010-05-27
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公开(公告)号： US08269012B2公开(公告)日： 2012-09-18
- 发明人: David Lauffer , Pan Li , Kira McGinty
- 申请人： David Lauffer , Pan Li , Kira McGinty
- 申请人地址： US MA Cambridge
- 专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人地址： US MA Cambridge
- 代理商 Daniel A. Pearson
- 主分类号： C07D215/12
- IPC分类号： C07D215/12 ; A61K31/47
摘要：
The present invention relates to compounds of formula I, which is useful in the inhibition of c-Met protein kinase. The invention also provides pharmaceutically acceptable compositions comprising compounds of formula I and methods of using the compositions in the treatment of proliferative disorders.