发明授权
- 专利标题： Glucokinase activators and methods of using same
- 专利标题（中）： 葡糖激酶活化剂及其使用方法
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申请号： US12871226申请日： 2010-08-30
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公开(公告)号： US08273777B2公开(公告)日： 2012-09-25
- 发明人: Yan Shi , Peter T. W. Cheng , Ying Wang , Denis E. Ryono
- 申请人： Yan Shi , Peter T. W. Cheng , Ying Wang , Denis E. Ryono
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Meyer Squibb Company
- 当前专利权人： Bristol-Meyer Squibb Company
- 当前专利权人地址： US NJ Princeton
- 代理商 Burton Rodney
- 主分类号： A61K31/4439
- IPC分类号： A61K31/4439 ; A61K31/426 ; C07D419/12 ; C07D277/56
摘要：
Compounds are provided which are activators of the enzyme glucokinase and thus are useful in treating diabetes and related diseases, which compounds have the structure where Q is and R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein or a pharmaceutically acceptable salt thereof. A method for treating diabetes and related diseases employing the above compounds is also provided.
公开/授权文献
- US20100324071A1 NOVEL GLUCOKINASE ACTIVATORS AND METHODS OF USING SAME 公开/授权日：2010-12-23