A load reduction system and method for use with memory systems which include one or more DIMMs, each of which includes a circuit arranged to buffer data bytes being written to or read from the DIMM, with the system nominally organized such that the bytes of a given data word are conveyed to the DIMMs via respective byte lanes and stored in a given rank on a given DIMM. The system is arranged such that the DRAMs that constitute a given rank are re-mapped across the available DIMMs plugged into the slots, such that a data word to be stored in a given rank is striped across the available DIMMs, thereby reducing the loading on a given byte lane that might otherwise be present. The system is preferably arranged such that any given byte lane is wired to no more than two of the DIMM slots.