Invention Grant
- Patent Title: Transition metal catalyzed synthesis of 2H-indazoles
- Patent Title (中): 过渡金属催化合成2H-吲唑
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Application No.: US12644371Application Date: 2009-12-22
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Publication No.: US08283476B2Publication Date: 2012-10-09
- Inventor: Nis Halland , Marc Nazare , Andreas Lindenschmidt , Jorge Alonso , Omar Rkyek , Matthias Urmann
- Applicant: Nis Halland , Marc Nazare , Andreas Lindenschmidt , Jorge Alonso , Omar Rkyek , Matthias Urmann
- Applicant Address: FR Paris
- Assignee: Sanofi
- Current Assignee: Sanofi
- Current Assignee Address: FR Paris
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: EP07290799 20070626
- Main IPC: C07D231/56
- IPC: C07D231/56
Abstract:
The present invention relates to a process for the regioselective synthesis of compounds of the formula I, wherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4, Q and J have the meanings indicated in the claims. The present invention provides a direct transition metal catalyzed process to a wide variety of multifunctional 2H-indazoles or 2H-azaindazoles of the formula (I) from 2-halo-phenylacetylenes or (2-sulfonato)phenylacetylenes and monosubstituted hydrazines.
Public/Granted literature
- US20100234601A1 Transition metal catalyzed synthesis of 2H-indazoles Public/Granted day:2010-09-16
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