发明授权
US08287871B2 Methods of inducing cell death of an activated T cell with anti-PSGL-1 antibodies
有权
用抗PSGL-1抗体诱导活化的T细胞的细胞死亡的方法
- 专利标题: Methods of inducing cell death of an activated T cell with anti-PSGL-1 antibodies
- 专利标题(中): 用抗PSGL-1抗体诱导活化的T细胞的细胞死亡的方法
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申请号: US12399484申请日: 2009-03-06
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公开(公告)号: US08287871B2公开(公告)日: 2012-10-16
- 发明人: Rong-Hwa Lin , Chung Nan Chang , Pei-Jiun Chen , Chiu-Chen Huang
- 申请人: Rong-Hwa Lin , Chung Nan Chang , Pei-Jiun Chen , Chiu-Chen Huang
- 申请人地址: NL Amsterdam
- 专利权人: AbGenomics Cooperatief U.A.
- 当前专利权人: AbGenomics Cooperatief U.A.
- 当前专利权人地址: NL Amsterdam
- 代理机构: Wolf, Greenfield & Sacks, P.C.
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/28
摘要:
Immunoglobulin chains or antibodies having light or heavy chain complementarity determining regions of antibodies that bind to P-Selectin Glycoprotein Ligand-1. Also disclosed are methods of inducing death of an activated T-cell and of modulating a T cell-mediated immune response in a subject.
公开/授权文献
- US20090191204A1 ANTI-PSGL-1 ANTIBODIES 公开/授权日:2009-07-30
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