发明授权
- 专利标题: PGDS as modifiers of the PTEN pathway and methods of use
- 专利标题(中): PGDS作为PTEN途径的修饰剂和使用方法
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申请号: US11628637申请日: 2005-06-20
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公开(公告)号: US08288119B2公开(公告)日: 2012-10-16
- 发明人: Chunyan Song , Michael Martin Ollmann , Lynn Margaret Bjerke
- 申请人: Chunyan Song , Michael Martin Ollmann , Lynn Margaret Bjerke
- 申请人地址: US CA South San Francisco
- 专利权人: Exelixis, Inc.
- 当前专利权人: Exelixis, Inc.
- 当前专利权人地址: US CA South San Francisco
- 代理机构: McDonnell Boehnen Hulbert & Berghoff LLP
- 国际申请: PCT/US2005/022087 WO 20050620
- 国际公布: WO2006/002250 WO 20060105
- 主分类号: C12Q1/32
- IPC分类号: C12Q1/32 ; C12N5/02
摘要:
Human PGD genes are identified as modulators of the PTEN pathway, and thus are therapeutic targets for disorders associated with defective PTEN function. Methods for identifying modulators of PTEN, comprising screening for agents that modulate the activity of PGD are provided.
公开/授权文献
- US20090019558A1 PGDS AS MODIFIERS OF THE PTEN PATHWAY AND METHODS OF USE 公开/授权日:2009-01-15
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