发明授权
US08288435B2 2-aza-bicyclo[3.1.0]hexane derivatives as orexin receptor antagonists
失效
2-氮杂 - 双环[3.1.0]己烷衍生物作为食欲素受体拮抗剂
- 专利标题: 2-aza-bicyclo[3.1.0]hexane derivatives as orexin receptor antagonists
- 专利标题(中): 2-氮杂 - 双环[3.1.0]己烷衍生物作为食欲素受体拮抗剂
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申请号: US12521453申请日: 2007-12-28
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公开(公告)号: US08288435B2公开(公告)日: 2012-10-16
- 发明人: Hamed Aissaoui , Christoph Boss , Markus Gude , Ralf Koberstein , Thierry Sifferlen , Daniel Trachsel
- 申请人: Hamed Aissaoui , Christoph Boss , Markus Gude , Ralf Koberstein , Thierry Sifferlen , Daniel Trachsel
- 申请人地址: CH Allschwill
- 专利权人: Actelion Pharmaceuticals Ltd.
- 当前专利权人: Actelion Pharmaceuticals Ltd.
- 当前专利权人地址: CH Allschwill
- 代理机构: Hoxie & Associates LLC
- 优先权: WOPCT/IB2006/055042 20061228
- 国际申请: PCT/IB2007/055326 WO 20071228
- 国际公布: WO2008/081399 WO 20080710
- 主分类号: A61K31/403
- IPC分类号: A61K31/403 ; C07D209/12
摘要:
The invention relates to novel 2-aza-bicyclo[3.1.0]hexane derivatives of Formula (I) wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.
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