发明授权
- 专利标题： Formulations of suberoylanilide hydroxamic acid and methods for producing same
- 专利标题（中）： 辛二酰苯胺异羟肟酸的制剂及其制备方法
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申请号： US12686812申请日： 2010-01-13
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公开(公告)号： US08288440B2公开(公告)日： 2012-10-16
- 发明人: Jeannie Chow Wong , Aaron S. Cote , Erik A. Dienemann , Kimberly Gallagher , Craig Ikeda , Justin Moser , Pavol Rajniak , Robert A. Reed , Cindy Starbuck , Hsien-Hsin Tung , Qingxi Wang , Benjamin Max Cohen , Vincent R. Capodanno , Brian Sell
- 申请人： Jeannie Chow Wong , Aaron S. Cote , Erik A. Dienemann , Kimberly Gallagher , Craig Ikeda , Justin Moser , Pavol Rajniak , Robert A. Reed , Cindy Starbuck , Hsien-Hsin Tung , Qingxi Wang , Benjamin Max Cohen , Vincent R. Capodanno , Brian Sell
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理商 Li Su; David A. Muthard
- 主分类号： A61K31/19
- IPC分类号： A61K31/19
摘要：
The present invention provides a pharmaceutical composition or crystalline composition with a specific dissolution profile, which comprises suberoylanilide hydroxamic acid or a pharmaceutically acceptable salt or hydrate thereof as an active ingredient. The present invention provides a process of producing said crystalline composition or pharmaceutical composition. The present invention also provides compositions with a specific particle size distribution.
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