发明授权
US08288550B2 Crystalline form of a benzimidazole-carboxamide medicinal compound
有权
苯并咪唑 - 甲酰胺药物化合物的结晶形式
- 专利标题： Crystalline form of a benzimidazole-carboxamide medicinal compound
- 专利标题（中）： 苯并咪唑 - 甲酰胺药物化合物的结晶形式
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申请号： US12948030申请日： 2010-11-17
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公开(公告)号： US08288550B2公开(公告)日： 2012-10-16
- 发明人: Sean M. Dalziel , Kirsten M. Phizackerley
- 申请人： Sean M. Dalziel , Kirsten M. Phizackerley
- 申请人地址： US CA South San Francisco
- 专利权人： Theravance, Inc.
- 当前专利权人： Theravance, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理商 Jeffrey A. Hagenah; Roberta P. Saxon
- 主分类号： C07D401/00
- IPC分类号： C07D401/00
摘要：
The invention provides crystalline forms of the novel benzimidazole-carboxamide 5-HT4 receptor agonist compound, 4-(4-{[(2-isopropyl-1H-benzoimidazole-4-carbonyl)amino]methyl}-piperidin-1-ylmethyl)piperidine-1-carboxylic acid methyl ester. The invention also provides pharmaceutical compositions comprising the crystalline compound, methods of using the compound to treat diseases associated with 5-HT4 receptor activity, and processes useful for preparing crystalline forms of the compound.
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