A programmable logic device can be configured as a fractional rate resampling filter capable of performing downsampling prior to upsampling without modifying the overall filter response. Input data may be received at a first sample rate and may be downsampled to generate downsampled data. Portions of the downsampled data may be respectively output to different filtering paths. Each filtering path may include a cluster of filter components that corresponds to different subfilters of the overall filter response and may be operable to receive and process the different portions of the downsampled data. Outputs of each cluster may be combined to generate output data at a second sample rate. The resampling filter structure can reduce the number of multiplier circuits used by allowing time-division multiplexing among different filter components.