发明授权
US08293911B2 Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators
有权
4-（正 - 氮杂环烷基）苯胺的衍生物作为钾通道调节剂
- 专利标题： Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators
- 专利标题（中）： 4-（正 - 氮杂环烷基）苯胺的衍生物作为钾通道调节剂
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申请号： US11894877申请日： 2007-08-22
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公开(公告)号： US08293911B2公开(公告)日： 2012-10-23
- 发明人: Jean-Michel Vernier , Martha Alicia De La Rosa , Huanming Chen , Jim Zhen Wu , Gary Lee Larson , Ian Wayne Cheney
- 申请人： Jean-Michel Vernier , Martha Alicia De La Rosa , Huanming Chen , Jim Zhen Wu , Gary Lee Larson , Ian Wayne Cheney
- 申请人地址： US CA Aliso Viejo
- 专利权人： Valeant Pharmaceuticals International
- 当前专利权人： Valeant Pharmaceuticals International
- 当前专利权人地址： US CA Aliso Viejo
- 代理机构： Jones Day
- 主分类号： C07D217/02
- IPC分类号： C07D217/02 ; C07D217/22 ; A61K31/472
摘要：
This invention provides a compound of formula IA where X═O or S; Y is O or S; q=1 or 0; and other substituents are defined herein. Such compounds can affect the opening of, or otherwise modulate, voltage-gated potassium channels. They are potentially useful for the treatment and prevention of diseases and disorders which are affected by activation or modulation of potassium ion channels. One such condition is seizure disorders.
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