Provided is a moisture retention seal for use with a package. The moisture retention seal includes an opened-ended canister having a plurality of canister sealing surfaces. Snap-fitted with spatial interference to the canister at its opened-end, is a moisture retention closure having a plurality of closure sealing surfaces. Each canister sealing surface cooperates with a corresponding one of the closure sealing surfaces to form a plurality of partial seals. At least one of the partial seals includes a micro-bead surface comprising one or more small, inwardly directed, narrowly spaced-apart, micro-bead elements. The package that includes a moisture retention seal of the present invention employs only molded parts and does not require gaskets or secondary seals.