Invention Grant
- Patent Title: Anti-IL-7 receptor antibodies
- Patent Title (中): 抗IL-7受体抗体
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Application No.: US13033491Application Date: 2011-02-23
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Publication No.: US08298535B2Publication Date: 2012-10-30
- Inventor: Chia-Yang Lin , Li-Fen Lee , Wenwu Zhai
- Applicant: Chia-Yang Lin , Li-Fen Lee , Wenwu Zhai
- Applicant Address: US CA South San Francisco
- Assignee: Rinat Neuroscience Corp.
- Current Assignee: Rinat Neuroscience Corp.
- Current Assignee Address: US CA South San Francisco
- Agent Susan L. Wang; Deborah A. Martin
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; C12N5/12
Abstract:
The present invention provides antagonizing antibodies that bind to interleukin-7 receptor (IL-7R). The invention further provides a method of obtaining such antibodies and antibody-encoding nucleic acids. The invention further relates to therapeutic methods for use of these antibodies and antigen-binding portions thereof for the treatment and/or prevention of type 2 diabetes and immunological disorders, including type 1 diabetes, multiple sclerosis, rheumatoid arthritis, graft-versus-host disease, and lupus.
Public/Granted literature
- US20110206698A1 ANTAGONIST ANTI-IL-7 RECEPTOR ANTIBODIES AND METHODS Public/Granted day:2011-08-25
Information query
