- 专利标题: Compounds having NPY Y5 receptor antagonistic activity
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申请号: US13354881申请日: 2012-01-20
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公开(公告)号: US08299066B2公开(公告)日: 2012-10-30
- 发明人: Masahiro Sakagami , Hiroshi Hashizume , Satoru Tanaka
- 申请人: Masahiro Sakagami , Hiroshi Hashizume , Satoru Tanaka
- 申请人地址: JP Osaka-shi
- 专利权人: Shionogi & Co., Ltd.
- 当前专利权人: Shionogi & Co., Ltd.
- 当前专利权人地址: JP Osaka-shi
- 代理机构: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- 优先权: JP2008-109778 20080421
- 主分类号: A61K31/536
- IPC分类号: A61K31/536 ; A61K31/4439 ; A61K31/40 ; A61K31/4174 ; A61K31/415 ; A61K31/4196 ; A61K31/404 ; A61K31/506 ; A61K31/497 ; A61K31/427 ; A61K31/422 ; A61K31/5377 ; A61K31/437 ; A61K31/519 ; A61K31/4985 ; A61K31/444
摘要:
This invention provides a compound of the formula (I): a pharmaceutically acceptable salt or solvate thereof, wherein R1 is substituted or unsubstituted alkyl or the like, R2 is hydrogen or substituted or unsubstituted alkyl, Ring A is monocyclic or bicyclic aromatic heterocycle, R3 is substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl or substituted or unsubstituted heterocycle, R4 is halogen, cyano, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl or the like, m is an integer between 0 and 2, n is an integer between 0 and 5, R is halogen, oxo, cyano, nitro, substituted or unsubstituted alkyl or the like, and p is an integer between 0 and 2 as novel compounds having NPY Y5 antagonistic activity.
公开/授权文献
- US20120130070A1 COMPOUNDS HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY 公开/授权日:2012-05-24
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