A technique migrates data from a source array to a target array while preserving SCSI reservation compliance. The technique involves providing an active-to-passive instruction to the source array while a first SCSI reservation enables hosts to access data on the source array using MPIO software. The active-to-passive instruction directs the source array to transition devices from active mode to passive mode and, upon receipt of a next SCSI instruction, output an indicator indicating that the first SCSI reservation has been cleared. The technique further involves transitioning devices of the target array from passive mode to active mode and beginning a data transfer operation which transfers data from the source array to the target array. The technique further involves automatically effectuating formation of a second SCSI reservation in place of the first SCSI reservation, the second SCSI reservation providing host access to the data on the target array using MPIO software.