A pneumatic tire comprising an air permeation preventive layer comprising a film of a thermoplastic resin composition containing a polyvinyl alcohol or ethylene vinyl alcohol copolymer, to which a protective film of a rubber composition containing an ethylene propylene rubber (EPM) or ethylene propylene diene rubber (EPDM) is, directly or via an adhesive, placed adjacent thereto, as one layer in at least one side thereof, whereby both a further reduction in the air leakage rate of the pneumatic tire and a good durability can be achieved and furthermore a reduction in the weight of the tire can be achieved.