发明授权
US08309350B2 Photoreactive regulator of protein function and methods of use thereof
有权
蛋白质功能的光反应性调节剂及其使用方法
- 专利标题： Photoreactive regulator of protein function and methods of use thereof
- 专利标题（中）： 蛋白质功能的光反应性调节剂及其使用方法
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申请号： US13364105申请日： 2012-02-01
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公开(公告)号： US08309350B2公开(公告)日： 2012-11-13
- 发明人: Ehud Y. Isacoff , Richard H. Kramer , Dirk Trauner , Matthew R. Banghart , Matthew Volgraf , Pablo Ignacio Gorostiza Langa , Katharine Borges
- 申请人： Ehud Y. Isacoff , Richard H. Kramer , Dirk Trauner , Matthew R. Banghart , Matthew Volgraf , Pablo Ignacio Gorostiza Langa , Katharine Borges
- 申请人地址： US CA Oakland
- 专利权人： The Regents of the University of California
- 当前专利权人： The Regents of the University of California
- 当前专利权人地址： US CA Oakland
- 代理机构： Bozicevic, Field & Francis LLP.
- 代理商 Paula A. Borden
- 主分类号： C12N5/00
- IPC分类号： C12N5/00 ; A61K38/00
摘要：
The present invention provides a synthetic regulator of protein function, which regulator is a light-sensitive regulator. The present invention further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present invention further provides methods of modulating protein function, involving use of light. The present invention further provides methods of identifying agents that modulate protein function.
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