发明授权
US08309584B2 Sulfur containing pyrazole-heterocycle derivatives as cannabinoid CB1 receptor antagonists
失效
含硫吡唑杂环衍生物作为大麻素CB1受体拮抗剂
- 专利标题： Sulfur containing pyrazole-heterocycle derivatives as cannabinoid CB1 receptor antagonists
- 专利标题（中）： 含硫吡唑杂环衍生物作为大麻素CB1受体拮抗剂
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申请号： US13120026申请日： 2008-09-25
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公开(公告)号： US08309584B2公开(公告)日： 2012-11-13
- 发明人: Jinhwa Lee , Hee Jeong Seo , Min-Ah Kim , Jeongmin Kim , Sung-Han Lee , Myung Eun Jung , Mi-Soon Kim
- 申请人： Jinhwa Lee , Hee Jeong Seo , Min-Ah Kim , Jeongmin Kim , Sung-Han Lee , Myung Eun Jung , Mi-Soon Kim
- 申请人地址： KR Yongin-si
- 专利权人： Green Cross Corporation
- 当前专利权人： Green Cross Corporation
- 当前专利权人地址： KR Yongin-si
- 代理机构： Sughrue Mion, PLLC
- 国际申请： PCT/KR2008/005689 WO 20080925
- 国际公布： WO2010/035915 WO 20100401
- 主分类号： A61K31/433
- IPC分类号： A61K31/433 ; A61K31/4245 ; A61P3/04 ; C07D413/04 ; C07D417/04
摘要：
A novel sulfur containing heteroaryl-pyrazole compound of formula (I) or a pharmaceutically acceptable salt thereof is effective as a cannabinoid CB1 receptor inverse agonist or antagonist, which is useful for preventing or treating obesity and obesity-related metabolic disorders. The prevention also provide a method for preparing same, a pharmaceutical composition containing same, and a method for preventing or treating obesity and obesity-related metabolic disorders.
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