- 专利标题: Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands
-
申请号: US12892402申请日: 2010-09-28
-
公开(公告)号: US08309609B2公开(公告)日: 2012-11-13
- 发明人: Torbjörn Lundstedt , Anna Skottner , Elisabeth Seifert
- 申请人: Torbjörn Lundstedt , Anna Skottner , Elisabeth Seifert
- 申请人地址: SE
- 专利权人: Anamar AB
- 当前专利权人: Anamar AB
- 当前专利权人地址: SE
- 代理机构: Bacon & Thomas, PLLC
- 优先权: GB0019357.3 20000807
- 主分类号: A61K31/55
- IPC分类号: A61K31/55 ; A01N37/52 ; A01N37/30
摘要:
The present invention relates to the use of compounds of general formula (I) as ligands to the melanocortin receptors and/or for treatment of disorders in the melanocortin system: wherein X is H or OH; R1, R2, R3, R4 and R5 are the same or different and are selected from hydrogen, halogen, alkyl having 1 to 5 carbon atoms, electron donor groups such as alkoxy having 1-5 carbon atoms or hydroxy, electron acceptor groups selected from cyano, nitro, trifluoroalkyl or amide; alkylamino, benzoyloxy, nitroxy, phenyl or sulpho; and the pharmacologically active salts thereof.
公开/授权文献
信息查询