A wake-and-go mechanism is provided with a central repository wake-and-go array for a multiple processor data processing system. The wake-and-go mechanism recognizes a programming idiom that indicates that a thread running on a processor within the multiple processor data processing system is waiting for an event. The wake-and-go mechanism updates a central repository wake-and-go array with a target address associated with the event. Each entry in the central repository wake-and-go array may include a thread identification (ID), a central processing unit (CPU) ID, the target address, the expected data, a comparison type, a lock bit, a priority, and a thread state pointer, which is the address at which the thread state information is stored.