发明授权
- 专利标题: Stabilization of poly(oxyalkylene) containing polymeric materials
- 专利标题(中): 含聚(氧化烯)的聚合材料的稳定化
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申请号: US12456409申请日: 2009-06-16
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公开(公告)号: US08318059B2公开(公告)日: 2012-11-27
- 发明人: Brian Gerrard Devlin , Arturo Norberto Medina , Karen Belinda Sentell , Stephen Raymond Perreault , Mireille Tena
- 申请人: Brian Gerrard Devlin , Arturo Norberto Medina , Karen Belinda Sentell , Stephen Raymond Perreault , Mireille Tena
- 申请人地址: CH Basel
- 专利权人: Novartis AG
- 当前专利权人: Novartis AG
- 当前专利权人地址: CH Basel
- 代理商 Jian Zhou
- 主分类号: B29C71/00
- IPC分类号: B29C71/00
摘要:
The present invention provides a method for producing a medical device, preferably an ophthalmic device, more preferably a contact lens, made of a stabilized poly(oxyalkylene)-containing polymeric material. The method of the invention comprises the steps of: curing, in a mold, a composition comprising (a) a prepolymer having at least one poly(oxyalkylene) unit, (b) a biocompatible organic multi-acid or biocompatible salt thereof in an amount sufficient to improve the stability of the poly(oxyalkylene)-containing polymer made from the composition, (c) optionally a photoinitiator or a thermal initiator, and (d) optionally one or more vinylic monomers, to form the medical device being less susceptible to oxidative degradation; and removing the medical device from the mold.
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