A system and method for BIOS and controller communication. An information handling system comprises a central processing unit coupled to a memory. The memory further comprises a BIOS. The information handling system further comprises a controller coupled to a nonvolatile memory, and a register coupled to the central processing unit and the controller. The controller is operable to initialize communication with the BIOS, and service commands from the BIOS. The central processing unit is operable to initialize communication with the controller, and send commands to the controller.A method for communication between a BIOS and a controller in an information handling system comprises initializing communication between the BIOS and the controller. The method further comprises encrypting a command using a key by the BIOS, and sending the command to the controller. The controller processes the command, and the BIOS receives the result.