发明授权
US08323661B2 Method for generating a stable recombinant modified vaccinia virus ankara (MVA) comprising human immunodeficiency virus (HIV) genes inserted into one or more intergenic regions (IGRs)
有权
用于产生包含插入到一个或多个基因间区域(IGR)中的人免疫缺陷病毒(HIV)基因的稳定的重组修饰的痘苗病毒安卡拉(MVA)的方法,
- 专利标题: Method for generating a stable recombinant modified vaccinia virus ankara (MVA) comprising human immunodeficiency virus (HIV) genes inserted into one or more intergenic regions (IGRs)
- 专利标题(中): 用于产生包含插入到一个或多个基因间区域(IGR)中的人免疫缺陷病毒(HIV)基因的稳定的重组修饰的痘苗病毒安卡拉(MVA)的方法,
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申请号: US13221108申请日: 2011-08-30
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公开(公告)号: US08323661B2公开(公告)日: 2012-12-04
- 发明人: Paul Howley , Sonja Leyrer , Paul Chaplin , Eva Felder
- 申请人: Paul Howley , Sonja Leyrer , Paul Chaplin , Eva Felder
- 申请人地址: DK Kvistgaard
- 专利权人: Bavarian Nordic A/S
- 当前专利权人: Bavarian Nordic A/S
- 当前专利权人地址: DK Kvistgaard
- 代理机构: Law Office of Salvatore Arrigo and Scott Lee, LLP
- 优先权: DK200200752 20020516; DK200200753 20020516; EP05004012 20050224
- 主分类号: A61K39/12
- IPC分类号: A61K39/12 ; A61K39/21 ; A61K39/275 ; C12N15/00
摘要:
The invention relates to novel insertion sites useful for the integration of HIV DNA sequences into the MVA genome, and to the resulting recombinant MVA derivatives.
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