发明授权
- 专利标题: Interaction of Moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system
- 专利标题(中): 卡他莫拉菌与上皮细胞,细胞外基质蛋白和补体系的相互作用
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申请号: US13314727申请日: 2011-12-08
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公开(公告)号: US08323667B2公开(公告)日: 2012-12-04
- 发明人: Arne Forsgren , Kristian Riesbeck
- 申请人: Arne Forsgren , Kristian Riesbeck
- 申请人地址: SE Falsterbo
- 专利权人: Arne Forsgren AB
- 当前专利权人: Arne Forsgren AB
- 当前专利权人地址: SE Falsterbo
- 代理机构: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- 主分类号: A61K39/02
- IPC分类号: A61K39/02 ; C07K14/195
摘要:
The present disclosure relates to surface proteins of Moraxella catarrhalis and their ability to interact with epithelial cells via cell-associated fibronectin and laminin, and also to their ability to inhibit the complement system. These surface proteins are useful in the preparation of vaccines. The present disclosure also provides peptides interacting with fibronectin, laminin and the complement system.
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