发明授权
- 专利标题: Methods of analysis of allelic imbalance
- 专利标题(中): 等位基因不平衡分析方法
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申请号: US13222851申请日: 2011-08-31
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公开(公告)号: US08323894B2公开(公告)日: 2012-12-04
- 发明人: Giulia C Kennedy
- 申请人: Giulia C Kennedy
- 申请人地址: US CA Santa Clara
- 专利权人: Affymetrix, Inc.
- 当前专利权人: Affymetrix, Inc.
- 当前专利权人地址: US CA Santa Clara
- 代理机构: Affymetrix, Inc.
- 主分类号: C07H21/04
- IPC分类号: C07H21/04 ; C12Q1/68
摘要:
Methods are provided for identification of genes that are imprinted. In another embodiment methods are provided for identification and analysis of genes whose expression shows allelic imbalance. The expression products transcribed from genes that are present in the genome as two or more alleles may be distinguished by hybridization to an array designed to interrogate individual alleles. Genes whose transcription products are present in amounts that vary from expected are candidates for allelic imbalance, imprinting and imprinting errors.
公开/授权文献
- US20110319273A1 Methods of analysis of allelic imbalance 公开/授权日:2011-12-29
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