发明授权
- 专利标题： Pyrimidyl cyclopentanes as Akt protein kinase inhibitors
- 专利标题（中）： 嘧啶环戊烷作为Akt蛋白激酶抑制剂
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申请号： US12812384申请日： 2009-01-09
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公开(公告)号： US08324221B2公开(公告)日： 2012-12-04
- 发明人: Anna L. Banka , James F. Blake , Josef R. Bencsik , Kin Chiu Fong , Martin F. Hentemann , Douglas M. Sammond , Ian S. Mitchell , Rui Xu , Eli M. Wallace , Tony Tang
- 申请人： Anna L. Banka , James F. Blake , Josef R. Bencsik , Kin Chiu Fong , Martin F. Hentemann , Douglas M. Sammond , Ian S. Mitchell , Rui Xu , Eli M. Wallace , Tony Tang
- 申请人地址： US CO Boulder
- 专利权人： Array Biopharma Inc.
- 当前专利权人： Array Biopharma Inc.
- 当前专利权人地址： US CO Boulder
- 代理机构： Viksnins Harris & Padys PLLP
- 国际申请： PCT/US2009/030603 WO 20090109
- 国际公布： WO2009/089454 WO 20090716
- 主分类号： A01N43/54
- IPC分类号： A01N43/54 ; A01N43/90 ; A61K31/517 ; A61K31/519 ; C07D239/70
摘要：
The present invention provides compounds of Formula (I) including tautomers, resolved enantiomers, resolved diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as Akt protein kinase inhibitors and for the treatment of Akt-mediated diseases, for example, hyperproliferative diseases such as cancer.
公开/授权文献
- US20110053959A1 PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS 公开/授权日：2011-03-03
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