Systems and methods for distributed management of keep-alive message signaling for mobile network resource conservation and optimization are disclosed. In one aspect, embodiments of the present disclosure include a method, which may be implemented on a system, of monitoring rates of data communications with a mobile device, sending a periodic message to indicate operational state to the mobile device in response to a decrease in the rates of data communications with the mobile device, sending subsequent periodic messages to indicate operational state to the mobile device at increasing intervals between the subsequent periodic messages to decrease a number of periodic messages sent over the wireless network, and acknowledging to the mobile device that the subsequent periodic messages will be sent at increased intervals, or in a manner that conserves use of the mobile network.