Disclosed herein is an electro-hydraulic brake system. The electro-hydraulic brake system includes a master cylinder to transmit brake oil, a high-pressure accumulator to transmit brake oil independently of the master cylinder, first and second circuits connected respectively to the master cylinder, at least one first wheel to be braked by the first circuit, and at least one second wheel to be braked by the second circuit. The first circuit is connected to the high-pressure accumulator, to control the first wheel. The second circuit is connected to the first circuit, to control the second wheel.