发明授权
- 专利标题: Pyrrolo-nitrogenous heterocyclic derivatives, the preparation and the pharmaceutical use thereof
- 专利标题(中): 吡咯 - 含氮杂环衍生物,其制备及其药物用途
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申请号: US12451466申请日: 2008-05-14
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公开(公告)号: US08329682B2公开(公告)日: 2012-12-11
- 发明人: Peng Cho Tang , Yidong Su , Yali Li , Lei Zhang , Fuqiang Zhao , Jialiang Yang , Ying Zhou , Pingyan Bie , Guangtao Qian , Minggang Ju
- 申请人: Peng Cho Tang , Yidong Su , Yali Li , Lei Zhang , Fuqiang Zhao , Jialiang Yang , Ying Zhou , Pingyan Bie , Guangtao Qian , Minggang Ju
- 申请人地址: CN Shanghai
- 专利权人: Shanghai Hengrui Pharmaceutical Co., Ltd.
- 当前专利权人: Shanghai Hengrui Pharmaceutical Co., Ltd.
- 当前专利权人地址: CN Shanghai
- 代理机构: MacDonald, Illig, Jones & Britton LLP
- 代理商 Jon L. Woodard
- 优先权: CN200710107463 20070514; CN200810087564 20080411
- 国际申请: PCT/CN2008/001352 WO 20080514
- 国际公布: WO2008/138232 WO 20081120
- 主分类号: C07D519/00
- IPC分类号: C07D519/00 ; C07D487/04 ; C07D471/04 ; A61K31/41 ; A61K31/437 ; A61P35/00
摘要:
The invention provides new pyrrolo-nitrogenous heterocyclic derivatives represented by formula (I) or their salts, the preparation thereof, pharmaceutical compositions containing such derivatives and the use of such derivatives as therapeutic agents, especially as protein kinase inhibitors, wherein each substituent in formula (I) is same as defined in the description.
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