Invention Grant
- Patent Title: Small molecule inhibitors of ghrelin O-acyltransferase
- Patent Title (中): 生长素释放肽O-酰基转移酶的小分子抑制剂
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Application No.: US13226471Application Date: 2011-09-06
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Publication No.: US08329745B2Publication Date: 2012-12-11
- Inventor: Patrcik G. Harran , Michael S. Brown , Joseph L. Goldstein , Jing Yang , Tong-Jin Zhao
- Applicant: Patrcik G. Harran , Michael S. Brown , Joseph L. Goldstein , Jing Yang , Tong-Jin Zhao
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agent Richard Aron Osman
- Main IPC: A61K31/4164
- IPC: A61K31/4164 ; A61K31/505 ; A61K31/27 ; A61K31/216 ; A61K31/165 ; C07D233/60 ; C07D239/26 ; C07C275/18 ; C07C271/22 ; C07C235/32
Abstract:
Ghrelin O-acyltransferase (GOAT) is inhibited with designed small molecules of the general formula: Methods comprise contacting the GOAT with an inhibitor and detecting a resultant inhibition.
Public/Granted literature
- US20110318807A1 Small Molecule Inhibitors of Ghrelin O-Acyltransferase Public/Granted day:2011-12-29
Information query
