发明授权
US08329912B2 Solid forms of 2-chloro-4-[1-(4-fluoro-phenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl]-pyridine
有权
固体形式的2-氯-4- [1-（4-氟 - 苯基）-2,5-二甲基-1H-咪唑-4-基乙炔基] - 吡啶
![Solid forms of 2-chloro-4-[1-(4-fluoro-phenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl]-pyridine](/docs/US/2012-12-11/US08329912B2/abs.jpg.600x600.jpg)
- 专利标题： Solid forms of 2-chloro-4-[1-(4-fluoro-phenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl]-pyridine
- 专利标题（中）： 固体形式的2-氯-4- [1-（4-氟 - 苯基）-2,5-二甲基-1H-咪唑-4-基乙炔基] - 吡啶
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申请号： US13273266申请日： 2011-10-14
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公开(公告)号： US08329912B2公开(公告)日： 2012-12-11
- 发明人: Thomas Cleary , Alexander Glomme , Olaf Grassmann , Shan-Ming Kuang , Roland Meier , Doreen Miller , Regina Moog , Franziska E. Rohrer , Jason Yang
- 申请人： Thomas Cleary , Alexander Glomme , Olaf Grassmann , Shan-Ming Kuang , Roland Meier , Doreen Miller , Regina Moog , Franziska E. Rohrer , Jason Yang
- 申请人地址： US NJ Nutley
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： US NJ Nutley
- 代理商 George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- 主分类号： C07D401/02
- IPC分类号： C07D401/02
![Solid forms of 2-chloro-4-[1-(4-fluoro-phenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl]-pyridine](/abs-image/US/2012/12/11/US08329912B2/abs.jpg.150x150.jpg)
摘要：
The present invention relates to mono-sulfate and hemi-sulfate salts of 2-Chloro-4-[1-(4-fluoro-phenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl]-pyridine, to crystalline and amorphous forms thereof and to their use in pharmaceutical formulations.
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