发明授权
- 专利标题： Dry powder medicament formulations
- 专利标题（中）： 干粉药剂配方
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申请号： US10489491申请日： 2002-09-16
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公开(公告)号： US08337816B2公开(公告)日： 2012-12-25
- 发明人: Andrew Bruce Brown , Michael Mary Van Oort
- 申请人： Andrew Bruce Brown , Michael Mary Van Oort
- 申请人地址： GB Greenforo, Middlesex
- 专利权人： Glaxo Group Limited
- 当前专利权人： Glaxo Group Limited
- 当前专利权人地址： GB Greenforo, Middlesex
- 代理商 Robert J. Smith
- 国际申请： PCT/US02/29267 WO 20020916
- 国际公布： WO03/024396 WO 20030327
- 主分类号： A61K9/00
- IPC分类号： A61K9/00 ; A61K9/14 ; A61K9/16
摘要：
A dry powder pharmaceutical composition comprising (i) a medicament particle fraction comprising medicament particles with an aerodynamic diameter no greater than 10 μm; and (ii) at least 50% of a non-respirable excipient fraction comprising low density excipient particles with an aerodynamic diameter greater than 10 μm and a geometric diameter greater than 30 μm. In additional embodiments of the invention, the pharmaceutical composition includes a respirable excipient fraction comprising excipient particles with an aerodynamic diameter no greater than 10 μm. In a preferred embodiment of the invention, the non-respirable excipient particles include pores adapted to receive a portion of the respirable excipient fraction and/or the medicament fraction.
公开/授权文献
- US20040241232A1 Dry powder medicament formulations 公开/授权日：2004-12-02
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