- 专利标题： Synthetic processes for the preparation of aminocyclohexyl ether compounds
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申请号： US13297846申请日： 2011-11-16
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公开(公告)号： US08344162B2公开(公告)日： 2013-01-01
- 发明人: Grace Jung , James Gee Ken Yee , Doug Ta Hung Chou , Bertrand M. C. Plouvier
- 申请人： Grace Jung , James Gee Ken Yee , Doug Ta Hung Chou , Bertrand M. C. Plouvier
- 申请人地址： CA Vancouver
- 专利权人： Cardiome Pharma Corp.
- 当前专利权人： Cardiome Pharma Corp.
- 当前专利权人地址： CA Vancouver
- 代理机构： Seed IP Law Group PLLC
- 主分类号： C07D207/40
- IPC分类号： C07D207/40 ; C07D207/416
摘要：
This invention is directed to stereoselective synthesis of compounds of formula (I) or formula (II): or a pharmaceutically acceptable salt, ester, amide, complex, chelate, clathrate, solvate, polymorph, stereoisomer, metabolite or prodrug thereof; wherein R3, R4 and R5 are defined herein. Compounds of formula (I) and formula (II) are known to be useful in treating arrhythmias.
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