A screw has a screw head and a shank. The screw head has a square cavity, a hexagonal cavity or a hexagonal boss to be wedged by a screw driver for wrenching. The shank has a first asymmetrical thread at the taper to facilitate drilling holes, asymmetrical saw-type threads behind the first asymmetrical thread, and a second asymmetrical thread behind the asymmetrical saw-type threads. The shank further has a carved V-shaped tail between the first asymmetrical thread and the asymmetrical saw-type threads to facilitate cutting and debris dispelling. The screw thus formed can rapidly perform thread tapping and debris dispelling, and reduce friction and expand drilling holes and achieve fast fastening.