The tamper evident cap assembly is structured for protective connection to a syringe of the type having a nozzle and a discharge port, wherein the cap assembly includes a body configured to receive and access to the nozzle. A flow restricting member is connected to the body to at least initially define a one piece construction. The flow restricting member is disposed in flow restricting relation to the discharge port of the nozzle. An attachment assembly interconnects the body and the flow restricting member and is structured, such as by being frangible to facilitate detachment of the body from the flow restricting member upon the body being removed from the syringe. A connecting assembly is structured for a snap-fit connection to the nozzle and retains the flow restricting member thereon upon removal of the body from the syringe.