Invention Grant
US08349294B2 Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
有权
用于药物递送的稳定的金属离子 - 脂质粉末药物组合物和使用方法
- Patent Title: Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
- Patent Title (中): 用于药物递送的稳定的金属离子 - 脂质粉末药物组合物和使用方法
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Application No.: US12967482Application Date: 2010-12-14
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Publication No.: US08349294B2Publication Date: 2013-01-08
- Inventor: Luis A Dellamary , Jean Riess , Ernest G Schutt , Jeffry G Weers , Thomas E Tarara
- Applicant: Luis A Dellamary , Jean Riess , Ernest G Schutt , Jeffry G Weers , Thomas E Tarara
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agency: Janah & Associates, P.C.
- Agent Guy V. Tucker
- Main IPC: A61K49/00
- IPC: A61K49/00 ; A61K9/127 ; A61K9/14 ; A61K9/50 ; A61B5/055
Abstract:
Microparticle compositions comprising metal ion-lipid complexes for drug delivery are described including methods of making the microparticle compositions and methods of treating certain conditions and disease states by administering the microparticle compositions. The metal ion-lipid complexes can be combined with various drugs or active agents for therapeutic administration. The microparticle compositions of the present invention have superior stability to other microparticle compositions resulting in a microparticle composition with longer shelf life and improved dispersability. The microparticle compositions of the present invention have a transition temperature (Tg) of at least 20° C. above the recommended storage temperature (Tst) for drug delivery.
Public/Granted literature
- US20110082076A1 STABLE METAL ION-LIPID POWDERED PHARMACEUTICAL COMPOSITIONS FOR DRUG DELIVERY AND METHODS OF USE Public/Granted day:2011-04-07
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