Invention Grant
- Patent Title: Stable and soluble antibodies inhibiting VEGF
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Application No.: US13000423Application Date: 2009-06-25
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Publication No.: US08349322B2Publication Date: 2013-01-08
- Inventor: Leonardo Borras , David Urech , Tea Gunde
- Applicant: Leonardo Borras , David Urech , Tea Gunde
- Applicant Address: CH Schlieren
- Assignee: ESBATech, an Alcon Biomedical Research Unit, LLC
- Current Assignee: ESBATech, an Alcon Biomedical Research Unit, LLC
- Current Assignee Address: CH Schlieren
- Agent Jason J. Derry
- International Application: PCT/CH2009/000220 WO 20090625
- International Announcement: WO2009/155724 WO 20091230
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00 ; C07K16/08 ; C07K16/22
Abstract:
The present invention relates to soluble and stable anti-VEGF immunobinders comprising CDRs from rabbit monoclonal antibodies. Said antibodies are designed for the diagnosis and/or treatment of VEGF-mediated disorders. The hybridomas, nucleic acids, vectors and host cells for expression of the recombinant antibodies of the invention, methods for isolating them and the use of said antibodies in medicine are also disclosed.
Public/Granted literature
- US20120014958A1 STABLE AND SOLUBLE ANTIBODIES INHIBITING VEGF Public/Granted day:2012-01-19
Information query
