Invention Grant
- Patent Title: Nucleic acid coated particles suitable for temporary storage
- Patent Title (中): 适用于临时储存的核酸涂层颗粒
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Application No.: US10529010Application Date: 2003-09-29
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Publication No.: US08349364B2Publication Date: 2013-01-08
- Inventor: Chris Robert Lively , Robert DeLong
- Applicant: Chris Robert Lively , Robert DeLong
- Applicant Address: GB Oxford
- Assignee: Powderject Research Limited
- Current Assignee: Powderject Research Limited
- Current Assignee Address: GB Oxford
- Agency: Foley & Lardner LLP
- International Application: PCT/GB03/04202 WO 20030929
- International Announcement: WO2004/028560 WO 20040408
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K9/16 ; A61K9/50 ; C12N15/87 ; C12N15/11 ; A61K48/00
Abstract:
Particles are provided which are suitable for delivery from a particle-mediated delivery device. The particles are obtained by precipitating a nucleic acid on inert metal carrier particles in the presence of a nucleic acid condensing agent and a metal ion chelating agent. Also described are processes for preparing the particles, and therapeutic methods using the particles including methods of nucleic acid immunization and gene therapy.
Public/Granted literature
- US20060153804A1 Nucleic acid coated particles Public/Granted day:2006-07-13
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