Invention Grant
- Patent Title: Galectin-3 cleavage as a marker for matrix metalloproteinase activity in cancer
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Application No.: US12316587Application Date: 2008-12-11
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Publication No.: US08349579B2Publication Date: 2013-01-08
- Inventor: Avraham Raz , Pratima Nangia-Makker , Rafael Fridman
- Applicant: Avraham Raz , Pratima Nangia-Makker , Rafael Fridman
- Applicant Address: US MI Detroit
- Assignee: Wayne State University
- Current Assignee: Wayne State University
- Current Assignee Address: US MI Detroit
- Agent C. Rachal Winger
- Main IPC: C12Q1/37
- IPC: C12Q1/37
Abstract:
Provided are differential antibodies recognizing the cleaved and non-cleaved forms of matrix metalloproteinases (MMPs), and methods of using the antibodies as surrogate diagnostic markers for the presence of active MMPs in cancer, such as growing breast cancers.
Public/Granted literature
- US20090269779A1 Galectin-3 cleavage as a marker for matrix metalloproteinase activity in cancer Public/Granted day:2009-10-29
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