Invention Grant
US08349596B2 Method for the enzymatic production of 2-hydroxy-2-methyl carboxylic acids
有权
2-羟基-2-甲基羧酸的酶促生产方法
- Patent Title: Method for the enzymatic production of 2-hydroxy-2-methyl carboxylic acids
- Patent Title (中): 2-羟基-2-甲基羧酸的酶促生产方法
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Application No.: US12950752Application Date: 2010-11-19
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Publication No.: US08349596B2Publication Date: 2013-01-08
- Inventor: Roland H Mueller , Thore Rohwerder
- Applicant: Roland H Mueller , Thore Rohwerder
- Applicant Address: DE Darmstadt
- Assignee: Evonik Roehm GmbH
- Current Assignee: Evonik Roehm GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: DE102006014167 20060324; DE102006017760 20060412
- Main IPC: C12P7/62
- IPC: C12P7/62 ; C12P7/40 ; C12P7/42 ; C12N9/10 ; C07H21/04 ; C07K1/00
Abstract:
Provided is a composition containing: an isolated and purified polypeptide containing the amino acid sequence of SEQ ID NO: 4; and/or a heterodimeric enzyme containing: the isolated and purified polypeptide containing the amino acid sequence of SEQ ID NO: 4; and an isolated and purified polypeptide containing the amino acid sequence of SEQ ID NO: 2. Also provided is a process for producing a 2-hydroxy-2-methyl carboxylic acid or a salt or ester thereof, wherein the process involves: contacting a 3-hydroxy carboxylic acid or a salt or ester thereof with the above-mentioned composition to produce the 2-hydroxy-2-methyl carboxylic acid or the salt or ester thereof.
Public/Granted literature
- US20110165640A1 METHOD FOR THE ENZYMATIC PRODUCTION OF 2-HYDROXY-2-METHYL CARBOXYLIC ACIDS Public/Granted day:2011-07-07
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