Invention Grant
US08349804B2 Bone graft and scaffolding materials immobilized with type I collagen binding peptides
有权
用I型胶原结合肽固定的骨移植物和脚手架材料
- Patent Title: Bone graft and scaffolding materials immobilized with type I collagen binding peptides
- Patent Title (中): 用I型胶原结合肽固定的骨移植物和脚手架材料
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Application No.: US12278009Application Date: 2007-01-19
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Publication No.: US08349804B2Publication Date: 2013-01-08
- Inventor: Yoon-Jeong Park , Chong-Pyoung Chung , Seung-Jin Lee , Jue-Yeon Lee
- Applicant: Yoon-Jeong Park , Chong-Pyoung Chung , Seung-Jin Lee , Jue-Yeon Lee
- Applicant Address: KR Seoul
- Assignee: Seoul National University Industry Foundation
- Current Assignee: Seoul National University Industry Foundation
- Current Assignee Address: KR Seoul
- Agency: Moore & Van Allen, PLLC
- Agent Andrew D. Gerschutz; Tristan A. Fuierer
- Priority: KR10-2006-0010712 20060203
- International Application: PCT/KR2007/000335 WO 20070119
- International Announcement: WO2007/089084 WO 20070809
- Main IPC: A61K38/10
- IPC: A61K38/10 ; A61K38/16

Abstract:
The present invention relates to a pharmaceutical composition comprising a bone graft material, a scaffold for tissue engineering applications and type I collagen Binding Peptides which have bone calcification-promoting peptides immobilized on the surface, and more particularly, to a bone graft material and a scaffold for tissue engineering applications (hereinafter, referred to as scaffold), which have peptides specifically binding with type I collagen immobilized on the surface, and pharmaceutical composition for recovering tissue regeneration containing type I collagen binding-inducing peptide. In the inventive bone graft material and scaffold for tissue engineering applications, the cells related to regeneration by collagen binding-inducing peptide adhered to the surface, promote an adhesion of type I collagen binding-inducing peptide (main ingredients of extracellular matrix) to increase differentiation rate into bone tissues, and promote a calcification which is last step of bone regeneration to maximize a tissue regeneration finally.
Public/Granted literature
- US20110045048A1 BONE GRAFT AND SCAFFOLDING MATERIALS IMMOBILIZED WITH TYPE I COLLAGEN BINDING PEPTIDES Public/Granted day:2011-02-24
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